PDE5 Inhibitors
How PDE5 Enzyme and PDE5 Inhibitors Cooperate
A specific phosphodiesterase type 5 enzyme also known as PDE5 enzyme is a chemical compound. It is a protein produced by human body in order to suppress another chemical known as nitric oxide (NO).
Nitric oxide relaxes and widens the arteries in the pelvic area increasing penile blood flow to the genitals, penis in men and vagina in women.
In other words, if PDE5 enzyme weren’t present in our bodies, we would experience constant erection in the genitals. PDE5 enzyme is like a regulator of the time and process of erection.
There is another group of chemicals known as PDE5 inhibitors. These chemicals (drugs) get into the body from outside and block PDE5 enzyme for a few hours. By this time nitric oxide has already accumulated itself in the arteries filling them with blood and leading to a successful erection.
In a while, as the action of PDE5 inhibitors ends, PDE5 enzyme continues to suppress nitric oxide narrowing the arteries in the genital area and decreasing penile blood flow which results in the loss of erection.
